Hotel Nikko OsakavsHotel Mystays Sakaisuji-Honmachi
Both hotels are praised by professional travelers. On balance, Hotel Nikko Osaka scores slightly higher than Hotel Mystays Sakaisuji-Honmachi. Hotel Nikko Osaka comes in at 76 with recommendations from 4 publications such as Michelin Guide, Lonely Planet and Insight Guides.
Hotel Nikko Osaka
 Insight Guides
 Fodor's
 Michelin Guide
 Lonely Planet
1-3-3 Nishi-Shinsaibashi, Chuo-ku, Osaka, Osaka Prefecture 542-0086
From $97/night
- Bar/Lounge
 - Hot Tub
 - Free Internet
 - Room Service
 - Laundry Service
 - Concierge
 
 "A world-class hotel with rates to match its sumptuous rooms,    restaurants and bars. Located in one of Osaka’s liveliest entertainment    districts." 
 "A striking white tower in the colorful Shin-sai-bashi district, the Nikko is within easy reach of shopping meccas like Amerika-mura." Full review
 "Midosuji, the famous shopping street on which the hotel fronts, is the motif for the Superior Floor, with ginkgo leaf coloured accents inspired by Midosuji creating a stylish interior." Full review
 "The Nikkō is a good central base in Minami and has direct access to Shinsaibashi subway station." Full review
Hotel Mystays Sakaisuji-Honmachi
 Oyster
1-4-8 Awajimachi, Chuo-ku, (Former Mystays Inn Sakaisuji-Honmach), Osaka, Osaka Prefecture 541-0047
From $30/night
- Hot Tub
 - Free Internet
 - Laundry Service
 - Laundy Room
 - Restaurant
 - Smoking Rooms
 
Mid-Range
 "There are 189 guest rooms at this three-pearl property set in a quiet, residential area of central Osaka." Full review