Hotel New Otani OsakavsShin-Osaka Station Hotel Honkan
Both hotels are highly recommended by those who travel for a living. Overall, Hotel New Otani Osaka is preferred by most professionals compared to Shin-Osaka Station Hotel. Hotel New Otani Osaka has a TripExpert Score of 79 with approval from 4 reviews including Michelin Guide, Lonely Planet and Fodor's.
Hotel New Otani Osaka
 Lonely Planet
 Fodor's
 Oyster
 Michelin Guide
1-4-1 Chuo-ku Shiromi, Osaka, Osaka Prefecture 540-8578
From $131/night
- Bar/Lounge
 - Hot Tub
 - Free Internet
 - Room Service
 - Shuttle Bus
 - Laundry Service
 
 "The sprawling hotel has one of the best hotel locations in all of Osaka." Full review
 "Indoor and outdoor pools, a rooftop garden, tennis courts, and a sparkling marble atrium make this hotel a popular choice for both Japanese and Western travelers." Full review
Upscale
 "The four-pearl Hotel New Otani Osaka is a massive multi-story hotel with 525 guest rooms located in a business district, a short walk from Osaka Castle (which is visible from some rooms)." Full review
 "The hotel is a 30-minute taxi ride from Osaka International Airport and Shin-Osaka Station, and there is a shuttle bus from Kansai International Airport." Full review
 i 
Try to get a room equipped with ‘bedroom environment systems’ for business travellers as they have massage chairs.
Shin-Osaka Station Hotel Honkan
 Lonely Planet
 Oyster
1-16-6 Higashinakajima, Higashiyodogawa-ku, Osaka, Osaka Prefecture 533-0033
From $45/night
- Hot Tub
 - Free Internet
 - Free Breakfast
 - Laundry Service
 - Laundy Room
 - Restaurant
 
 "Five minutes from Shin-Osaka Station, this efficiently run hostel is in a large building with great views... Private rooms are good value, with one designated room for the physically disabled." 
Budget
 "The 75-room Shin-Osaka Station Hotel is a two-and-a-half-pearl property situated a short walk from the Shin-Osaka JR station." Full review